行情

KPTI

KPTI

Karyopharm
NASDAQ

实时行情|Nasdaq Last Sale

15.88
-0.63
-3.79%
盘后: 15.90 +0.03 +0.16% 17:48 01/27 EST
开盘
15.89
昨收
16.50
最高
16.44
最低
15.77
成交量
87.82万
成交额
--
52周最高
20.09
52周最低
3.920
市值
9.97亿
市盈率(TTM)
-4.6373
分时
5日
1月
3月
1年
5年

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所属板块

生物技术和医学研究
-0.88%
制药与医学研究
-0.51%

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KPTI 简况

Karyopharm Therapeutics Inc. is an oncology-focused pharmaceutical company. The Company is focused on the discovery, development, and commercialization of drugs directed against nuclear export and related targets for the treatment of cancer and other diseases. Its selective inhibitor of nuclear export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Its lead compound, XPOVIOTM (selinexor), received accelerated approval from the Food and Drug Administration (FDA), in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. Its XPOVIO is an oral SINE compound, which blocks the nuclear export of tumor suppressor, growth regulatory and anti-inflammatory proteins, leading to accumulation of these proteins in the nucleus and enhancing their anti-cancer activity in the cell. It is also focused on developing treatments for other diseases, such as Hematologic Malignancies and Solid Tumor Malignancies.
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