Calithera

CALA NASDAQ
4.740
-1.060
-18.28%
盘后: 4.500 -0.24 -5.06% 19:49 06/18 EDT
开盘
5.13
昨收
5.80
最高
5.43
最低
4.630
成交量
187.73万
成交均量(3M)
18.76万
52周最高
6.90
52周最低
3.550
换手率
4.78%
市值
1.86亿
分时
5日
1月
3月
1年
5年

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公司介绍

Calithera Biosciences, Inc. is a clinical-stage pharmaceutical company. The Company focuses on discovering and developing small molecule drugs directed against tumor and immune cell targets that control key metabolic pathways in the tumor microenvironment. It is engaged in developing agents that take advantage of the metabolic requirements of tumor cells and cancer-fighting immune cells, such as cytotoxic T-cells. The Company's lead product candidate, CB-839, is a critical enzyme in tumor cells. Its other product candidate, CB-1158, is being developed for hematology and oncology indications. CB-1158 is a potent and selective orally bioavailable inhibitor of the enzyme arginase. CB-839 is a selective, reversible and orally bioavailable inhibitor of human glutaminase. CB-1158 has single agent anti-tumor activity in syngeneic mouse tumor models that has been demonstrated to act through an immune mechanism. CB-1158 is being tested in a Phase I clinical trial in patients with solid tumors.
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