Novabridge Biosciences is a global biotechnology platform company. The Company combines deep business development expertise with agile translational clinical development to identify, accelerate, and advance breakthrough assets. Its segments include oncology and ophthalmology. The oncology segment focuses on the research and development of precision immuno-oncology agents for the treatment of cancer. The ophthalmology segment focuses on research and development of ophthalmologic indications such as wet age-related macular degeneration (Wet AMD) and diabetic macular edema (DME). Its differentiated pipeline includes givastomig, a bispecific antibody (Claudin 18.2 x 4-1BB), and VIS-101, a bifunctional biologic, targeting VEGF-A and ANG2. Givastomig conditionally activates T cells via the 4-1BB signaling pathway in the tumor microenvironment where Claudin 18.2 is expressed. VIS-101 targets VEGF-A and ANG-2 to provide more potent treatment benefits for patients with wet AMD and DME.