Omada Health To Present Published Research Showing That Members Of Its GLP-1 Care Track Lost More Weight And Experienced Greater Improvements In Body Composition Than GLP-1 Users Receiving Usual Care

GLP-1 medications can produce rapid weight loss,2 but lean mass can account for 30% or more of the weight lost.3,4 Lean mass is critical for overall health, as losing lean mass may contribute to reductions in resting metabolic rate5, impaired physical function and greater susceptibility to weight regain,6 as well as an increased risk for sarcopenia,7 frailty, and bone loss.6,8 While exercise and resistance training are known to be effective strategies for increasing fat loss while protecting lean mass,¹ much less is known about whether virtual care programs can improve body composition outcomes for people taking GLP-1 medications.

The study followed 245 adults with obesity who had started a GLP-1 for weight loss within the previous eight weeks.¹ Of those, 151 participated in Omada's GLP-1 Care Track and 94 received usual care, which could include medication alone or other, non-Omada lifestyle programs. More than a quarter (26%) of the usual care group reported using another lifestyle or wellness program during the study.¹

After 12 weeks, compared with the usual care group, Omada members on average:¹

Lost more weight (6.0% of starting body weight vs. 3.3%)
Reduced their body fat percentage by about twice as much (−3.3% vs. −1.6%)
Saw a larger increase in muscle mass percentage (+0.6% vs. +0.2%)
Reported greater improvements in well-being, physical functioning, and confidence in their ability to lose weight
Saw depression and anxiety symptoms drop by roughly 30%, significantly more than the usual care group

The GLP-1 Care Track provides clinical support between doctor visits. Members work with a care team that includes a dedicated health coach, GLP-1-specific peer support groups, digital tools for meal logging and behavior tracking, and AI-powered nutrition support.¹ The program also includes access to an exercise specialist who provides a personalized exercise plan developed by a physical therapist. Participants measured body composition at home using bioelectrical impedance scales.