J&J says Phase 3 ICONIC-LEAD trial shows ICOTYDE sustains plaque psoriasis clearance through 2 years

PUBT · 2d ago
J&J says Phase 3 ICONIC-LEAD trial shows ICOTYDE sustains plaque psoriasis clearance through 2 years
  • Johnson & Johnson disclosed new two-year Phase 3 ICONIC-LEAD results for oral psoriasis drug ICOTYDE, already presented at Fall Clinical Dermatology 2026.
  • Study showed durable skin clearance and sustained itch improvement in adults and adolescents through two years of treatment.
  • Patients who stopped therapy and later restarted generally regained strong disease control within months.
  • Safety profile remained consistent over two years, with no new safety concerns flagged.


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