argenx says Phase 2 trial shows FB102 significantly improves Vh:Cd ratio in celiac disease gluten challenge

PUBT · 3d ago
argenx says Phase 2 trial shows FB102 significantly improves Vh:Cd ratio in celiac disease gluten challenge
  • argenx reported positive topline Phase 2 results for FB102 in celiac disease, supporting a move into Phase 3 development.
  • Patients on FB102 showed reduced gluten-driven intestinal injury versus placebo during a controlled gluten challenge.
  • Broad secondary measures aligned with the main outcome, including inflammation signals and patient-reported symptoms.
  • No new safety concerns emerged; the safety profile matched prior studies.
  • Detailed Phase 2 data will be presented at a future medical meeting.


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