Chugai licenses RAF-MEK molecular glue SPYK04 to InxMed in worldwide deal

PUBT · 2d ago
Chugai licenses RAF-MEK molecular glue SPYK04 to InxMed in worldwide deal
  • Chugai Pharmaceutical licensed SPYK04 to InxMed under an exclusive worldwide deal covering development, manufacturing, commercialization for solid-tumor indications.
  • Chugai to receive an upfront payment, sales-based royalties post-launch, profit share on non-royalty income InxMed collects from sublicensees.
  • SPYK04 is a RAF-MEK “molecular glue” designed to induce an inactive RAF-MEK complex, aiming to block cancer-cell proliferative signaling.


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