Veloxis doses first patient in Phase 2 kidney transplant trial of pegrizeprument (VEL-101)

PUBT · 3d ago
Veloxis doses first patient in Phase 2 kidney transplant trial of pegrizeprument (VEL-101)
  • Veloxis Pharmaceuticals, part of Asahi Kasei, dosed the first patient in the Phase 2 RENGEVITY-201 trial of pegrizeprument (VEL-101).
  • The study tests pegrizeprument as a maintenance immunosuppressant to prevent organ rejection in de novo kidney transplant recipients.
  • RENGEVITY-201 plans to enroll up to 120 patients, randomizing them 1:1:1 to two pegrizeprument doses or tacrolimus.
  • Primary endpoints focus on safety, pharmacokinetics, pharmacodynamics, with efficacy assessed versus tacrolimus.


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