Celldex posts investor presentation highlighting barzolvolimab late-stage chronic urticaria program milestones

PUBT · 1d ago
Celldex posts investor presentation highlighting barzolvolimab late-stage chronic urticaria program milestones
  • Celldex outlined a late-stage immunology pipeline centered on barzolvolimab, a KIT antagonist antibody targeting mast cells.
  • Phase 3 CSU program enrollment completed 6 months ahead of guidance; topline data expected in Sept/Oct 2026.
  • Topline readout set to cover both EMBARQ-CSU trials, Week 12 primary endpoint, safety through Week 24.
  • Phase 3 ColdU/SD study initiated in Dec 2025; Phase 2 atopic dermatitis study fully enrolled with topline data expected late 2026.
  • CDX-622 bispecific targeting TSLP and SCF posted positive Phase 1 healthy-volunteer data; Phase 1 asthma proof-of-mechanism study started Jan 2026.


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