Xintela publishes Phase I/IIa data showing XSTEM improves pain, function in knee osteoarthritis study

PUBT · 3d ago
Xintela publishes Phase I/IIa data showing XSTEM improves pain, function in knee osteoarthritis study
  • Xintela published peer-reviewed Phase I/IIa results for XSTEM in knee osteoarthritis in the journal Cartilage; results were previously presented in September 2025.
  • The study showed the treatment was well tolerated, with no serious treatment-related safety issues reported.
  • Patients reported reduced knee pain and improved joint function, supporting a potential disease-modifying effect.
  • The highest dose showed sustained improvements in cartilage and bone tissue quality for up to two years, with signs of slowing cartilage breakdown.
  • Publication increases visibility of the dataset for potential partners, strengthening the investment case for further development.


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