Neurocrine launches Phase 1 trial of NBIP-1968 triple-agonist obesity drug

PUBT · 1d ago
Neurocrine launches Phase 1 trial of NBIP-1968 triple-agonist obesity drug
  • Neurocrine began a Phase 1 first-in-human study of NBIP-'1968, a long-acting GLP-1/GIP/glucagon receptor triple agonist for obesity.
  • Initial Phase 1 work tests single ascending doses in adults across BMI categories, including overweight and obese, focusing on safety and tolerability.
  • Program targets once-weekly subcutaneous dosing; designed with balanced glucagon activity to improve metabolic benefit while supporting tolerability.
  • NBIP-'1968 is intended for fixed-dose combination with NBIP-'2118, a separate obesity candidate already in Phase 1 development.


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