Climb Bio initiates Phase 2 CLYM116 trial in IgA nephropathy in Q3 2026

PUBT · 2d ago
Climb Bio initiates Phase 2 CLYM116 trial in IgA nephropathy in Q3 2026
  • Climb Bio flagged initial Phase 1 data for anti-APRIL antibody CLYM116 in healthy volunteers for presentation on Sept. 3, 2026.
  • Early safety results for CLYM116 were already presented in June, supporting continued development in IgA nephropathy without raising new tolerability concerns.
  • Dosing is expected to start in Q3 2026 in a Phase 2 IgA nephropathy study run by partner Beijing Mabworks.
  • Budoprutug programs remain on track, with additional study readouts expected in Q4 2026 across kidney disease, ITP, and SLE.


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