Faron reports median overall survival not reached in BEXMAB trial for frontline higher-risk MDS patients without TP53 mutations

PUBT · 2d ago
Faron reports median overall survival not reached in BEXMAB trial for frontline higher-risk MDS patients without TP53 mutations
  • Faron Pharmaceuticals reported an initial overall-survival readout from the Phase 1/2 BEXMAB trial in frontline higher-risk MDS.
  • Survival appeared most encouraging in patients without TP53 mutations or with monoallelic TP53 mutations, with outcomes still developing.
  • Patients with biallelic TP53 mutations showed survival broadly consistent with prior experience in this aggressive subgroup.
  • Detailed results will be presented at a scientific meeting later in 2026 as follow-up continues.
  • Data support preparations for BEXERA, a planned randomized study of bexmarilimab with azacitidine in frontline higher-risk MDS.


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