Palisade Bio Secures Up To $500K Strategic Investment From The Crohn's & Colitis Foundation, To Advance PALI-2108 For Ulcerative Colitis And Fibrostenotic Crohn's Disease

Benzinga · 5d ago

PALI-2108 is the first and only PDE4 inhibitor in development designed for targeted delivery to the terminal ileum and colon, addressing significant unmet needs in ulcerative colitis (UC) and fibrostenotic Crohn's disease (FSCD)

 

Carlsbad, CA, Jan. 07, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (NASDAQ:PALI) ("Palisade" or the "Company"), a clinical-stage biopharmaceutical company developing next-generation, once-daily, oral PDE4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon, today announced that the Crohn's & Colitis Foundation (the "Foundation"), through its IBD Ventures program, has approved a strategic equity investment of up to $500,000 in Palisade. The investment will support the continued clinical and mechanistic development of PALI-2108, the Company's lead gut-microbiota-activated PDE4 inhibitor, being advanced for fibrostenotic Crohn's disease (FSCD) and moderate to severe ulcerative colitis (UC).