Novo Nordisk study links Wegovy to greater weight loss than resmetirom in adults with MASH

PUBT · 1d ago
Novo Nordisk study links Wegovy to greater weight loss than resmetirom in adults with MASH
  • Novo Nordisk announced real-world study results linking Wegovy to improved liver enzymes, weight and blood sugar in adults with MASH.
  • Results from PLATINUM-Truveta and RHODIUM-2 were presented at the American Association for the Study of Liver Diseases meeting in Denver in 2026.
  • PLATINUM-Truveta linked Wegovy to greater reductions in weight, blood sugar and a liver enzyme than resmetirom at six months.
  • RHODIUM-2 found greater improvements in liver enzymes, weight and blood sugar over one year versus patients who did not initiate semaglutide.
  • Both studies were retrospective and observational, meaning the findings establish associations rather than prove treatment effects.


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