Ascentage Pharma Publishes Presentation on APG-5918 T-Cell Lymphoma Study

PUBT · 19h ago
Ascentage Pharma Publishes Presentation on APG-5918 T-Cell Lymphoma Study
  • Ascentage Pharma published an announcement outlining clinical and preclinical data selected for the ASH annual meeting, December 12-15, 2026.
  • APG-5918's first clinical data will receive an oral presentation, showing a 44.7% objective response rate among 47 evaluable relapsed/refractory T-cell lymphoma patients.
  • At 600 mg daily, APG-5918 achieved a 65% objective response rate among 20 evaluable patients; disease control reached 95%.
  • No dose-limiting toxicities occurred during dose escalation, supporting 600 mg daily as the recommended Phase 2 dose.
  • Olverembatinib combined with lisaftoclax achieved complete remission in nine of 10 evaluable pediatric patients with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.


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