Calithera

CALA NASDAQ
3.820
-0.030
-0.78%
After Hours: 3.820 0 0.00% 16:00 08/23 EDT
Open
3.830
Prev Close
3.850
High
3.930
Low
3.760
Volume
265.22K
Avg Vol (3M)
437.87K
52 Week High
6.90
52 Week Low
3.430
% Turnover
0.49%
Market Cap
205.42M
1D
5D
1M
3M
1Y
5Y

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Company Profile

Calithera Biosciences, Inc. is a clinical-stage pharmaceutical company. The Company focuses on discovering and developing small molecule drugs directed against tumor and immune cell targets that control key metabolic pathways in the tumor microenvironment. It is engaged in developing agents that take advantage of the metabolic requirements of tumor cells and cancer-fighting immune cells, such as cytotoxic T-cells. The Company's lead product candidate, CB-839, is a critical enzyme in tumor cells. Its other product candidate, CB-1158, is being developed for hematology and oncology indications. CB-1158 is a potent and selective orally bioavailable inhibitor of the enzyme arginase. CB-839 is a selective, reversible and orally bioavailable inhibitor of human glutaminase. CB-1158 has single agent anti-tumor activity in syngeneic mouse tumor models that has been demonstrated to act through an immune mechanism. CB-1158 is being tested in a Phase I clinical trial in patients with solid tumors.
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