Sunshine Biopharma Inc. (NASDAQ: "SBFM" and SBFMW) (the "Company" or "Sunshine Biopharma"), a pharmaceutical company focused on the research, development and commercialization of oncology and antiviral drugs today announced that it has agreed to provide additional resources to the University of Arizona R. Ken Coit College of Pharmacy for the purposes of accelerating the development of novel PLpro inhibitors currently underway. The development of the Company's lead PLpro inhibitor, SBFM-PL4, is continuing in parallel.
At the University of Arizona Health Sciences, Gregory Thatcher, PhD, a professor of pharmacology and toxicology and the R. Ken and Donna Coit Endowed Chair of Drug Discovery, is leading the research effort that is progressing as planned. He is focused on determining the safety, pharmacokinetics and dose selection properties of three university-owned PLpro inhibitors, to be followed by efficacy testing for SARS-CoV-2 in animal models.
"With the transmissibility of the new Omicron variants (BA.4 and BA.5) approaching, and possibly exceeding that of measles (the most transmissible virus known to date), it is urgent that effective treatments and more specific vaccines be developed at an accelerated pace," said Dr. Steve Slilaty, CEO of Sunshine Biopharma. "We are delighted to be working with Dr. Gregory Thatcher, who is aiming to find a wide array of inhibitors for PLpro, as this virus encoded protease is responsible for suppression of the human immune system thereby enabling the virus to cause severe illness," he added.