The driving protein travels through the microtubule “track” in the cell and transports various nutrients to every corner of the cell, and is known as the “freight train” within the cell. Japan's Juntendo University recently issued a press release saying that researchers at the university and other institutions have discovered a mechanism that drives protein 1 to regulate blood sugar. Researchers found that in pancreatic beta cells, driver protein 1 directly controls the role of partner proteins on the endoplasmic retina, so that calcium channel protein can fold properly, thereby promoting insulin secretion. In other words, driver protein 1 plays an important role in calcium channel protein folding. Partner proteins are proteins that help other macromolecular structures fold or assemble. Calcium channel protein is responsible for regulating the transport of calcium ions and helps promote insulin secretion. According to the communiqué, pancreatic beta cells can sense changes in blood sugar, and an increase in blood sugar after meals will promote pancreatic beta cells to secrete insulin. Insulin is essential for maintaining blood sugar stability. However, in diabetics, this mechanism is disrupted, causing blood sugar to rise. This study confirmed that driver protein 1 has a new function in preventing diabetes and helps develop new treatments for diabetes. The relevant research paper has been published in the international journal “European Molecular Biology Organization Newsletter”.

The driving protein travels through the microtubule “track” in the cell and transports various nutrients to every corner of the cell, and is known as the “freight train” within the cell. Japan's Juntendo University recently issued a press release saying that researchers at the university and other institutions have discovered a mechanism that drives protein 1 to regulate blood sugar. Researchers found that in pancreatic beta cells, driver protein 1 directly controls the role of partner proteins on the endoplasmic retina, so that calcium channel protein can fold properly, thereby promoting insulin secretion. In other words, driver protein 1 plays an important role in calcium channel protein folding. Partner proteins are proteins that help other macromolecular structures fold or assemble. Calcium channel protein is responsible for regulating the transport of calcium ions and helps promote insulin secretion. According to the communiqué, pancreatic beta cells can sense changes in blood sugar, and an increase in blood sugar after meals will promote pancreatic beta cells to secrete insulin. Insulin is essential for maintaining blood sugar stability. However, in diabetics, this mechanism is disrupted, causing blood sugar to rise. This study confirmed that driver protein 1 has a new function in preventing diabetes and helps develop new treatments for diabetes. The relevant research paper has been published in the international journal “European Molecular Biology Organization Newsletter”.